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WELCOME!

Many of you arriving on this page from our Trim Healthy community might be wondering, “WHAT IS KIAORA?”

KIAORA (kee-your-ah) is a mission birthed out of the hearts of Pearl and Serene to serve our community in the area of hormone optimization. We have been working around the clock to get that ready for you…

We're excited to announce that our GLP-1 peptide therapy has launched and is available now! Our full line of hormone therapies will be launching later this year.

The name KIAORA holds a very special place in our hearts, as it was the name Serene had picked out for one of her precious babies that she lost to miscarriage. Although she didn’t get to hold that baby in her arms, the name and its beautiful meaning never left her.

KIAORA translates to “have life” or “be healthy” in the Maori language of their native land – New Zealand. It is the way you would greet someone. KIAORA wishes the essence of life upon someone!  “KIAORA!” So, what a fitting name for our next venture as we continue to live out our heart’s desire to serve our community by bringing health to every area of our lives.

THM $100 DISCOUNT CODE for GLP-1 Peptide Therapies!

Sign up with your email to get your $100 THM discount code on our GLP-1 peptide therapies AND to receive ongoing updates and information on the upcoming Hormone Replacement Therapy program launch.

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Ignite your body’s trimming hormone...

Cutting edge peptide therapy to reach your natural healthy weight

Healthy diet combined with the help of GLP-1.

Currently NOT Accepting Residents of California.

We’re excited to share something…

Some of you may have already heard that we are on the cusp of rolling out a complete medical program that will serve our community in all areas relating to women’s hormone health. What many of you may not be aware of is that we have also been doing extensive research around peptide therapies (GLP-1). Peptides are hormones too, they’re just smaller. Through this research and direct experience, we are ready to help certain people in a new way.

Through nearly 15 years of the Trim Healthy movement, we have always endeavored to keep ourselves at the intersection of ancient wisdom and groundbreaking science that has transformed so many lives. People have shed anywhere from a few pounds to hundreds of pounds, eating the Trim Healthy way, but more importantly, they have reclaimed control over their overall health and wellness.

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But if you're doing this and still struggling—working tirelessly but not yet witnessing the life-changing results you see others getting, know that you have continually been on our hearts and minds. You yearn for success but you feel like your body is so broken it can’t get there. Or, maybe you're just feeling stalled out in your journey… you’ve entered a new hormonal stage and boy have things changed! The Trim Healthy Plan will always be bedrock foundation but we are committed to bringing you some new tools in this next phase of hormone and peptide optimization.

When Effort Doesn't Equal Success

We know for some of you, it’s not for a lack of trying. The reality is that you may be dealing with metabolic challenges that others don't face. We’re ready to break down barriers that others in alternative health and wellness won't. We’ll face push back but we believe an integrative approach to optimal health is how more women (and men) can find breakthroughs.

Marrying Science and Lifestyle

We're going to be pushing boundaries, merging cutting-edge science with foundational nutrition to bring real solutions, including talking openly about the role GLP-1 peptide therapies can play in your health journey. And although these therapies won’t be for everyone (most people don’t need them), we know they can be potentially life changing for a smaller group of people who feel constantly left behind.

Enter Medication: A Taboo Subject?

Medication for weight loss can be a divisive topic. Lots of different opinions are being voiced in the media. Some are touting their benefits… others are warning against them. You hear about scary side effects… that these therapies are unnecessary… that results can be achieved through diet and exercise alone if someone puts in enough effort… and that if you go off them… you’ll gain all the weight back and more. There is also a general skepticism from many of us who are “crunchy” and have a leeriness of physician prescribed meds overall.

But while the stigma persists—that you should simply try harder, eat less, take this or that supplement, and exercise more—we know otherwise. We've worked with people who give it their all, yet due to genetic issues or severe insulin resistance or hormonal mayhem, they still struggle. This includes members of our own family!

We first became interested in these therapies back in 2020 when we heard about them on some biohacking/longevity groups we are members of. They were pretty much an unknown at that point for weight loss (they’d been around for over a decade for blood sugar regulation). The following year we attended a peptide, hormone and longevity convention with practitioners from all over the country. The spotlight beamed on these therapies and their positive effect on metabolic disorders. Although they are termed “medications” since they require a physician to be involved, they are based on a naturally occurring peptide we all make. The problem is some of us make less of it than others. People who make less are typically the ones who struggle more metabolism-wise. GLP - 1 (Glucagon Like Peptide) is a naturally occurring hormone in the body that is secreted after eating. Among the many functions it performs, perhaps the three most powerful are insulin regulation, blood sugar control and appetite satiety.

At that conference the side effects many hear about were explained… the slow gastric emptying can be mediated by dose. The thyroid cancer studies were on rats - in humans, that cancer is a very rare, genetic one that most people are not at risk for. There was some very encouraging research presented indicating these medications are actually powerful cancer fighters due to their blood sugar regulating effects and that they show benefits for those with cardiovascular and kidney issues. We realized the huge impact they could have and became personally involved by getting Sam, Serene’s husband treated with one of them.

Sam’s Story

Sam’s family has some genetic issues that are very challenging. Sam was one of those ones… no matter what he did… his body kept slowly gaining weight. He was a generally healthy eater but it was only when he was super strict that he could perhaps lose just a few pounds, but then all weight loss would stop and those pounds would come right back on again. As he entered his mid to late forties, his body became inflamed, his insulin jumped up, his A1C became pre-diabetic and his inflammation markers were far from optimal. Most people putting in the work he did would be trim and healthy. He’d tried so many things that didn’t work that he started to lose hope.

Sam’s turn around using these therapies has been amazing. His blood work dramatically improved. His reasons for going on the therapy were to get healthier… to get his insulin resistance and inflammation down. That happened but he also shed the stubborn weight. Weight loss was not his main goal but it was a definite side benefit. He kept eating the Trim Healthy way but this time it worked for his body. Sam learned GLP-1 therapies are best used with a low and slow approach. Many of the issues associated with these medications are from the standard titration dosing… which is much higher than most people require.

Introducing Dr. Kay Chandler (Surgeon General of the State of Arkansas): The Expert Behind the Science

Dr. Kay is a  distinguished OBGYN with nearly 30 years of experience and is the lead physician on our medical advisory board.

Dr. Kay demystifies therapies like GLP-1 —once only used for diabetes, but now approved for weight issues. She clarifies how these therapies, including semaglutide and tirzepatide, enhance the body's natural peptide production to better regulate insulin, blood sugar and hunger cues. She has an entirely new approach to using them safely and soundly.

But Who Really Benefits?

There is much talk about “food noise” with these therapies and how they help quell the constant desire to eat. Yes, they can help people experience feeling properly full when they’ve never really known that feeling, but they also help many without that issue. Dr. Kay finds these therapies are especially helpful for women dealing with polycystic ovarian syndrome, (PCOS ) of which 1 in 10 women suffer in the US, and they have been beneficial for many with extreme insulin resistance and malfunctioning metabolisms.

While these therapies have been sensationalized in the media of late because they have been abused with too swift and too high doses in order for people to shed weight very quickly… that will NEVER be the Trim Healthy approach. GLP-1 therapies can only be a long term solution if combined with the safe guidelines of wise eating (such as the Trim Healthy Plan). Wise eating and wise movement are foundational. When these therapies are used only to enable people to eat less but still unhealthfully, they fix nothing! They cause a state of skinny fat. The Trim Healthy approach with Dr. Kay is for these therapies to be wisely guided by medical professionals rather than handed out like candy at Med Spas and promoted to people just looking to get bikini bod shredded in 30 days. They will be used to create a lean mean fat burning body machine that retains and even builds body mass. The goal is to wean off them when the time is right and with greater lean body mass… not gain the weight back.

What About the Risks?

Yes, side effects exist. Rapid weight loss can lead to physical problems, but with a properly managed plan emphasizing protein along with intake of essential amino acids, clean foods and strength training, risks can be mitigated and even eliminated entirely. Digestive upsets can occur too but these can be better managed with wise dosing.

The Five Golden Rules from Dr. Kay
1. Low and Slow: Start with the lowest effective dose and stay there for as long as you are seeing baby step results.
2. Don’t skip meals: Make sure you’re getting enough nutrition in every meal even if your meals are smaller.
3. Be a Protein Nerd: Aim for 25 grams of protein per meal or snack and get that four times per day.
4. Be Mindful: Don't misuse these powerful therapies as an excuse to eat devitalized carbs and not enough protein.
5. Strength Training: Incorporate it three times a week, focusing on large muscle groups.

Real Life Transformation: A Patient’s Story

Dr. Kay was skeptical of these therapies at first, but she recalls her turning point moment when one of her patients—a busy mom with PCOS—who tried every imaginable diet plan and exercised religiously asked her to prescribe one for her. Despite her dedication, she had seen little to no results and went to bed hungry just to maintain her weight. Dr. Kay agreed with the stipulation they were not to be used as a quick fix, wise diet and movement would need to stay prioritized and titration would be only if needed and extremely conservative. With these measures in place, not only did this woman lose 30 pounds, she also felt stronger, more energetic, and most importantly, more confident. She finally felt like she was no longer broken metabolically.

Finding Hope in the Struggle

If you’re in a similar struggle, it isn't necessarily a sign of failure; it could be a call for a more personalized solution. If you relate to some of what we are sharing here, don’t lose hope. This could be the beginning of a whole new leg of your journey. Remember, this journey is not just about losing weight; that’s just icing on the healthy cake. The cake itself is losing inflammation, gaining confidence, strength, and overall vitality by giving your body the GLP -1 peptide it has been missing.

~Pearl & Serene

Millions...

Each year millions of Trim Healthy Products are purchased to support a natural journey to healthy weight.

500k+

Hundreds of thousands of women & families have experienced greater health and weight-loss by following Trim Healthy Principles. However some have been left behind.

Thousands...

The group who have struggled with hormonal and metabolic issues are now realizing they can achieve their healthiest weight through the combination of peptide therapies and the Trim Healthy Plan.

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Thousands of people are losing weight with GLP-1 therapy

Hear it from our Trim Healthy members, who have experienced life changing transformations through GLP-1 therapy.

4.8
1.2K REVIEWS

What is GLP-1?

GLP-1 is a hormone that regulates blood sugar levels and can be effective for weight loss due to the impact on appetite regulation and satiety. Here are some of the ways GLP-1 therapy contributes to weight loss.

Blood Sugar Balance

GLP-1 Therapies enchance glycemic control, which can support overall metabolic function and aid in reaching your healthiest weight.

Reset Appetite

GLP-1 Therapies act on the brain’s appetite centers, reducing the desire to overeat, promoting healthier eating habits.

Insulin Regulation

GLP-1 Therapies improve insulin efficiency, which helps to reduce consistently high insulin levels. This makes it easier for your body to shed fat.

what our customers
are saying

It's not just about the scale- it's about the life you gain.

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I was struggling gaining weight while doing my E’s and my S’s till I heard about Glp-1s. My doctor prescribed Tirzepatide (Mounjaro). I was on the shots for 10 months, lost around 40 pounds. I reached below my goal weight and I decided to stop and still continue with my Trim Healthy Mama foundation. I’m on maintenance, lifting weights and adding THM ESSENTIAL(essential amino acid poweder forumula) to help me tone my muscles. I’m 44 and I’ve never felt so young!

Photo of Customer Magaly Weaver
Magaly Weaver
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In May of 2022 I was 202 pounds and was diagnosed with high blood pressure, high cholesterol, and high blood sugar and had no energy. I had tried many different diets and was lightly exercising and walking with little to no results. I did microbiome study and took supplements which cleaned up my gut, yet I was frustrated with not losing the weight. That’s when I was prescribed the GLP-1 therapy. Finally I had success and was able to go from 202 to 150 pounds. I came off all blood pressure meds and all my levels stabilized and I am maintaining a size 8 for the first time in 20 years!  It helped me with the cravings, and yes, it suppressed my appetite but I never skipped a meal! I am happier, healthier, leaner and more energetic than ever!

Photo of customer Becki W.
Becki Walton
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I am 64 years old and I had started to put on some weight the last few years due to stress and hormonal loss. I was eating the Trim Healthy way, but I was stuck. My doctor prescribed semaglutide. My GLP-1 journey certainly hasn’t been a quick fix. I’ve been slow & steady for 6 months and have lost 38 pounds. I still eat my E’s, S’s & FP’s but in smaller meals & smaller portions making sure I get in my lean protein to help hold onto my muscle. I’m happy with my progress. I see my waist again and clothes I haven’t worn in 9 years fit! I weigh more than I did 9 years ago but my body composition is so different! I’m happy with my slow & steady transformation!

Photo of Customer Robin F
Robin Farmer

If you decide GLP-1 therapy is right for you, you have two options

VS

Semaglutide

(same active ingredient as Ozempic/Wegovy)
TAKE THE ASSESSMENT→
Currently NOT Accepting Residents of California
Better value
Great for most people
Some people experience nausea
GLP-1 receptor agonist

Tirzepatide

(same active ingredient as Mounjaro)
TAKE THE ASSESSMENT→
Currently NOT Accepting Residents of California
More Expensive
More Effective for some people
Less nausea
GLP-1/GIP dual receptor agonist

Our GLP-1 Therapies vs Brand Names (Ozempic/Mounjaro etc.)

Let's compare...

Semaglutide and Tirzepatide are essentially the same therapies as Ozempic/Wegovy/Mounjaro—they all contain the same active ingredient, function similarly, and yield comparable positive outcomes.

So why the significant price difference? When you opt for branded therapy like Ozempic or Wegovy, you're also footing the bill for the manufacturer's R&D and marketing endeavors, making the actual cost of the therapy a minor part of the overall price.

Moreover, most insurance policies don't include coverage for weight loss treatments, forcing individuals to either shell out $1,000 to $1,500 per month from their own pockets or navigate a cumbersome insurance appeals procedure.

We're advocates for making weight loss assistance both cost-effective and easily accessible.

Our GLP-1 Therapies vs Brand Names (Ozempic/Wegovy/Mounjaro)

Let's compare...

Semaglutide and Tirzepatide are essentially the same therapies as Ozempic/Wegovy/Mounjaro—they all contain the same active ingredient, function similarly, and yield comparable positive outcomes.

So why the significant price difference? When you opt for branded therapy like Ozempic or Wegovy, you're also footing the bill for the manufacturer's R&D and marketing endeavors, making the actual cost of the therapy a minor part of the overall price.

Moreover, most insurance policies don't include coverage for weight loss treatments, forcing individuals to either shell out $1,000 to $1,500 per month from their own pockets or navigate a cumbersome insurance appeals procedure.

We're advocates for making weight loss assistance both cost-effective and easily accessible.

Similarities
Ozempic/Wegovy
Semaglutide
Active
ingredient
semaglutide
semaglutide
Mechanism
of action
mimics the human hormone GLP-1 suppressing the appetite
mimics the human hormone GLP-1 suppressing the appetite
Frequency
once-week subcutaneous injection
once-week subcutaneous injection
Weight-loss
results
up to 20% of initial body weight
up to 20% of initial body weight
Differences
Ozempic/Wegovy
Semaglutide
Form
semaglutide
semaglutide
Doses
mimics the human hormone GLP-1 suppressing the appetite
mimics the human hormone GLP-1 suppressing the appetite
Price per 1 month Supply for off-label weight loss
$1200 - $1500
out of pocket (off-label use isn't covered by insurance)
$199-$399 (you pay for the therapy itself)

What you also get...

GLP-1 peptide therapy

Physician review

Therapies shipped right to your door

Additional Bonuses

2x TH Certified Coaching Sessions 

$240
Free

GLP-1 “essential toolbelt”

TH Basics for GLP-1
TH Meal Building Blocks For GLP-1
TH Jam Packed Possibilities Menu (GLP-1)
TH Starter Book (GLP-1)
TH Foundational Menu (GLP-1)
TH Food Lists (GLP-1)

$57
Free
Currently NOT Accepting Residents of California

A holistic approach to health

TAKE THE ASSESSMENT→
Currently NOT Accepting Residents of California

Optimizing your natural biology with GLP-1 therapy is simply the first chapter. We will help you address  all areas of your lifestyle to craft a personalized wellness journey, guided by medical expertise but aligned with your holistic values.

Nutrition
Physical Activity
Mindset
Community
Encouragement
Education

How it works

1

Fill out your Intake Assessment

This helps identify the most suitable therapy options
for your needs

2

Physician Evaluation

Get an efficient clinical evaluation from a licensed physician at NVP Medical Group

3

Receive Your Therapy

If approved by the treating physician, your GLP-1 therapy supplies will be delivered right to your doorstep.

TAKE THE ASSESSMENT→
Currently NOT Accepting Residents of California

FAQ

FAQ Expanded

Why is the dose in units, and how much medication am I getting?

The reason your practitioner uses units for dosing is that it is very easy for you to draw up the exact number of units on a syringe. Check out the chart below to find out how units convert to milligrams based on the strength:

Semaglutide

Dose
Tier 1 Semaglutide
10 units
20 units
Tier 2 Semaglutide
29 units
36 units
Tier 3 Semaglutide
40 units
48 units
Milligrams
(2.5mg/mL)
0.25 mg
0.50 mg
(2.5mg/mL)
0.72 mg
0.90 mg
(2.5mg/mL)
1 mg
1.2 mg

Tirzepatide

Dose
Tier 1 Tirzepatide
25 units
37 units
Tier 2 Tirzepatide
53 units
65 units
Tier 3 Tirzepatide
80 units
Milligrams
(10mg/mL)
2.45 mg
3.65 mg
(10mg/mL)
5.25 mg
6.5 mg
(10mg/mL)
8 mg
What does the sign-up and brief assessment look like?

The sign-up and quiz are quick and easy. First, you will fill out the questionnaire by answering a few medical and health history questions. You will then be directed to send us a copy of your state-provided ID for identity verification, which will complete your file. You will select either semaglutide or tirzepatide as your therapy of choice and place your order. Upon completion, a physician will review the information, confirm that you qualify for treatment, and start the prescription and shipping process.

What is included in the GLP-1 program?

Your GLP-1 program begins with a short questionnaire to confirm your compatibility with the program. If eligible based on your responses, you will then choose your payment plan preference for your prescription. The physician will review your answers and your choice of GLP-1 medication. If your prescription is approved, it will be sent to the pharmacy. The medication, syringes, and alcohol swabs will then be shipped to your door via express free shipping. You will also receive information on the product and the process of administering your medication (which is also available on the Kiaora website). In addition to this you can enjoy access to premium education, content, and recipes. You can also choose to redeem two free coaching sessions from one of our TH certified coaches when you place your first order.

How do billing and re-orders work?

At the time you place your order, if you choose the monthly payment plan, you will be billed the first installment for your 12 week prescription. The second installment will be charged 4 weeks after doctor approval and the third installment will be charged 8 weeks after doctor approval. If you choose to pay every 3 months, you will be charged the full payment at the time you place your order for the 12 week prescription. The charge will be refunded if you are not approved for the program.
When your prescription is due to renew, you will be prompted via email to renew your Rx in your patient portal. You will then need to confirm your patient information and a physician from the medical team will review your file. Once the review is approved, your next prescription will then be shipped. If your dose needs to be increased and is approved by the physician, your new Rx with the increased dose will be sent to the pharmacy and shipped to your door.

What is GLP-1?

Glucagon-like peptide-1 (or GLP-1) is a naturally occurring hormone in the body that is secreted in the gut and targets multiple receptors throughout the body related to appetite and hunger.

Among the many functions GLP-1 performs in the body, perhaps the three most powerful are insulin regulation, blood sugar control, and appetite suppression. When it comes to appetite, this can be why some people tend to overeat while others have more of an instinct about when to stop. The person putting down their fork may have greater natural levels of GLP-1 while the one going back for seconds may have less of this hormone, or may simply be  less sensitive to it.

What is GLP-1 therapy? (semaglutide & tirzepatide)

GLP-1 therapy is a breakthrough treatment for obesity and type 2 diabetes. They belong to a class of drugs known as GLP-1 Receptor Agonists and Incretin Mimetics. Semaglutide and tirzepatide are among the newer GLP-1’s, however the first therapy in this class was FDA approved in 2005 for the treatment of Type 2 diabetes (so these therapies have been around for almost 20 years).

If our bodies produce GLP-1 naturally, why would some need GLP-1 therapy for weight loss?

The natural function of GLP-1 is short-lived in the body. It pulses during and after eating, and then quickly subsides. Some of us naturally produce less GLP-1 than others, which can make it more difficult to maintain a healthy weight. Studies have also shown declining levels of GLP-1 in fasting serum in aging populations. This peptide therapy helps our bodies to recognize the “full” signal to the brain and slows emptying of the stomach, which results in a more efficient processing of our food as well as a reduction in cravings.

How do GLP-1 therapies work in the body exactly?
  • GLP-1 therapies activate gut hormone receptors in the pancreas, which allows greater uptake of blood sugar by the cells after a meal
  • GLP-1 inhibits glucagon secretion from the pancreas. Glucagon is an important and necessary hormone, but you don’t want the liver to overproduce it after eating, as this can cause excess weight gain
  • GLP-1 slows digestion and gastric emptying, which prolongs the feeling of “fullness” after a meal
  • GLP-1 regulates the brain’s hunger signals, resulting in a sense of satisfaction with fewer calories
How much weight should you lose on a GLP-1 product?

This will be unique for each person, however the “lose as much weight as quickly as possible” approach will never be the Kiaora way. While there are published trials demonstrating very rapid weight loss using GLP-1 therapies, this course of action requires high dosages and typically increases the likelihood of negative side-effects. The doctors we work alongside recommend a measured approach by starting at the initial dosage and increasing monthly until the weight loss reaches an optimal level. Even if you do not see drops on the scale every single week, positive shifts will likely be happening in your insulin production, blood sugar levels and overall inflammation. A slower but steady path to weight loss is much healthier for your body. Rapid weight loss depletes muscle mass swiftly and can be taxing to your liver.

How quickly do GLP-1 products produce weight loss?

GLP-1 therapies can produce rapid weight loss for some people of two to three pounds per week when used in high doses. But when this type of rapid weight loss occurs the body goes into a catabolic state, and a significant loss of muscle can occur along with the loss of fat. Other contributors to the very rapid weight loss some achieve with these medications are from a lack of protein and/or skipped meals due to doses that cause extreme appetite suppression. Once again, this often results in muscle loss and other gastro-intestinal issues. The best results are not the fastest results. Try to ignore the temptation to “keep up with the Joneses” so to speak. Others who are on higher doses and losing more than one pound per week may gush about their success, but you don’t want that because it only looks like success, when in reality it is not. Let your body shed fat safely and steadily while keeping muscle. This will not look like multiple pounds lost every single week but even on low doses, many see excellent results. To avoid that catabolic state, it’s crucial to have a low and slow approach along with a wise diet (one that does not pull out any food groups or meals), ample protein, and a minimum of three days a week of strength training.

What’s the difference between semaglutide and tirzepatide and which therapy is better for weight loss?

Semaglutide was the first GLP-1 therapy to become sensationalized in the drug market and was initially used as an effective therapy for diabetes. Millions of people began using semaglutide for diabetes and many began to find that they were losing weight. Since then, another peptide therapy called tirzepatide has gained great popularity, not only for its increased weight loss and blood sugar success, but also because of diminished common side effects such as nausea and other digestion issues. Tirzepatide targets weight loss not only through the GLP-1 mechanism but also through GIP (glucose-dependent insulinotropic peptide). Basically, tirzepatide has double action and is also called a “twincreatin” therapy as it mimics two groups of hormones which makes it more effective for many (but also more expensive).

Can I take a GLP-1 weight loss product if I am not a diabetic?

The FDA approved the use of GLP-1 therapies as an adjunct for weight management in individuals without diabetes, but only when used in conjunction with other weight-loss measures and with a doctor's supervision. GLP-1 therapy can aid in the treatment of obesity when used in conjunction with evidence-based lifestyle treatments like better nutrition and exercise.

Is this therapy likely to make me feel low on energy?

Some people may experience lower levels of energy, especially at higher doses which can cause an unhealthy calorie deficit. This is one of the reasons we recommend 4 protein-centered fuelings per day, being sure not to exclude healthy carbs such as fruit, sweet potatoes, beans, legumes, and whole grains from your diet.

Will I be hungry?

GLP-1 therapies can cause significant appetite suppression for many people. It’s important that you stay on as low a dose as your medical practitioner feels provides you just the right amount of suppression, and not so much that you are skipping meals or completely forgetting to eat. Your meals will likely be smaller than what you’ve been used to eating due to some appetite suppression, so be sure they contain adequate nutrition. Some people make the mistake of eating smaller portions of unhealthy food, but you want to be sure to eat healthy foods so that you can receive adequate nutrition in smaller meals.

What can I eat?

Focus on small meals that contain lean protein. At all costs, you must avoid losing more muscle mass while you lose fat! Adequate protein will be crucial to ensure this muscle wasting doesn’t happen… an adequate amount of protein is roughly 25 - 30 grams per meal. You may also want to consider the leucine content of your protein. Without sufficient leucine (one of the 9 essential amino acids) you cannot protect or build your lean body mass. Your body needs a minimum of 2 grams of leucine in a protein serving but 3 is optimal. If you can, make use of our ESSENTIAL (amino acid protein formula). This is a powder that you simply mix with water and drink. It gives you the bioequivalence of 90 grams of protein per serving with a full 3-gram bolus of leucine. Since the amino acids bypass digestion and go straight to your muscles, none of the protein is wasted or stored as fat. ESSENTIAL or any of our other Optimized proteins which contain a 3-gram leucine bolus per serving will ensure against muscle wasting. When you can’t think of eating much, just taking a drink of ESSENTIAL will make certain you get all your protein needs filled.

Do I have to eat healthy?

These therapies work best when paired with healthy eating. Eating fried foods or sugar-filled foods can cause gastrointestinal side effects to worsen for many. Just because semaglutide and tirzepatide tend to lower appetite, don’t fall into the trap of thinking you can now eat small amounts of devitalized foods and be fine. Yes, you still might lose weight this way, but it is not a healthy approach.

Should I skip meals?

Your appetite may be reduced as the emptying of your stomach slows. If you have suffered from “food noise” where your brain constantly thinks about food, this may diminish or completely subside. As your desire for food diminishes, you don’t have to eat huge meals… but don’t skip meals just because you don’t feel your regular amount of hunger. Skipping meals causes a state of LEA (low energy available) and also lowers leptin and thyroid hormones. Even though your meal portions may be smaller, it is important to include ample protein at every meal, as well as to choose from healthy carbs or healthy fats. Using semaglutide or tirzepatide as a way to intermittent fast can be dangerous, as it can harm your metabolism by causing potentially dangerous loss of muscle.

Why not jump up quickly to a higher dose?

As mentioned earlier, rapid weight loss can be harmful to the body. Recent research has revealed something called “weight loss injury” which occurs when the outer covering of fat cells (known as the outer cellular matrix) is forced to purge its stores quickly. Weight loss injury results in a stiffening effect on the fat cell, and it no longer works like a healthy one, becoming inflexible. This stiffening along with a loss of lean body mass, due to the absence of adequate calories and protein, is brutal to long-term metabolism. Body composition can begin to rearrange to higher fat levels and lower lean muscle tissue. There might be a lot of success on the scale, but the reality is “skinny fat” with depleted leptin and thyroid levels to boot. Keeping to a moderate dose that produces steady weight loss, reduces these negative effects and is the wiser approach when using these therapies in the most body-honoring and healthful way.

Can I stay at a particular dose without increasing?

Absolutely. If you are doing well at a lower dose, you can stay at that dosage level.

What if I miss a dose?

If you miss a dose of your GLP-1 medication and the next scheduled dose is more than 2 days away, administer it as soon as possible, then adjust your weekly dose accordingly. If you miss a dose, and the next scheduled dose is less than 2 days away, skip the missed dose and go back to your regular dosing schedule. If you miss a dose of this medicine for more than 2 weeks, use it on the next scheduled dose. You can also ask your doctor about how to restart your treatment.

How long do I need to take GLP-1 therapies for weight loss?

The duration of treatment with GLP-1 therapies for weight loss will depend on your individual needs and goals. In clinical trials, treatment typically lasted for 68 weeks, but some patients may continue treatment for longer periods of time in order to maintain weight loss.

Patients with less weight to lose, or who are more disciplined about combining GLP-1 therapies with a healthy diet and exercise may reach their target weight much sooner! If you are diligent about protecting and building your lean body mass (ie – muscle) through protein fueling and strength training while using these therapies, it is possible you may no longer need them once you are at your target weight. However, everyone is different, and some people may need to stay on a small maintenance dose.

Will I need to work out?

Weight training, along with about four protein fuelings a day will be very important in protecting your lean body mass. Weight training is encouraged, especially targeting your glutes and lower body for two days and upper body for the other day. Walking is encouraged for two more days per week if you can find the time, but the most important exercise sessions while on these therapies are the weight training.

Are GLP-1 therapies safe?

GLP-1 therapies are considered safe and effective when used as directed. But safe doesn’t mean that there aren’t risks. GLP-1 therapies also carry a boxed warning about thyroid C-cell tumors occurring in rodents (with unknown risk in humans), therefore GLP-1 therapies shouldn’t be used if you or your family have a history of a rare thyroid cancer known as Medullary thyroid cancer. GLP-1 therapies should not be used in people with type-1 diabetes or a history of pancreatitis. GLP-1 therapies may not be right for people on certain other blood sugar-lowering medications.

How is GLP-1 Therapy administered?

GLP-1 therapy is administered as a subcutaneous injection – “shot” – which is typically given in the fat of the abdomen or thigh once a week. It is done with a very small insulin syringe and is usually rather painless and not difficult to do.

What are the possible risks of GLP-1 therapies?

Get emergency medical help if you have signs of an allergic reaction: hives, itching; dizziness, fast heartbeats; difficulty breathing; swelling of your face, lips, tongue, or throat. Vision changes; unusual mood changes, thoughts about hurting yourself; pounding heartbeats or fluttering in your chest; a light-headed feeling, like you might pass out; signs of a thyroid tumor--swelling or a lump in your neck, trouble swallowing, a hoarse voice, feeling short of breath; symptoms of pancreatitis--severe pain in your upper stomach spreading to your back, nausea with or without vomiting, fast heart rate; gallbladder problems--upper stomach pain, fever, clay-colored stools, jaundice (yellowing of the skin or eyes); low blood sugar--headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; kidney problems--swelling, urinating less, feeling tired or short of breath

What are the side effects of GLP-1 shots?

Because GLP-1 therapies mimic the body’s natural peptides, imitating a hormone that the body produces naturally, it is generally considered quite safe and well tolerated – when prescribed by a qualified physician as part of a balanced weight loss plan.

The most common side effects include nausea, diarrhea, vomiting, and constipation. Other possible side effects include abdominal pain, decreased appetite, headache, and fatigue.

These side effects typically subside over time, as the patient’s body becomes used to the therapies and they learn the routine of the new reduced fat and caloric intake. Also, there are fewer instances of these side effects with tirzepatide than with semaglutide.

It is important to stay well hydrated with plenty of water (not sugary drinks like sodas or fruit juice). Eat fiber rich foods, healthy proteins and leafy greens and other veggies to combat digestion issues. If needed, teas such as Smooth Move may be helpful if constipation occurs.

If nausea becomes a problem – contact your physician through your patient portal; there are anti-nausea medications they can prescribe that are highly effective.

Can GLP-1 therapies be used in combination with other weight-loss medications?

Most patients who are prescribed GLP-1 therapies find that they do not need additional weight management meds.

GLP-1's should not be used in combination with other GLP-1 receptor agonists or therapies that increase GLP-1 receptor activity. GLP-1 therapies can be used in combination with other weight loss medications, but the safety and efficacy of such combinations have not been studied and needs to be addressed with your physician.

Can I take my medication(s) while on GLP-1 therapies?

Most medications do not interfere with GLP-1 therapies. However, we suggest that you discuss this therapy with your physician, as with any medication.

Can I take Semaglutide or Tirzepatide if I am pregnant or breastfeeding?

There is limited information available about the safety of these therapies during pregnancy or breastfeeding. Pregnant and breastfeeding women will be excluded from Kiaora’s therapy at this time. If you become pregnant while on therapy, please contact the medical staff through your online patient portal.

Can GLP-1 therapies be used by people with diabetes?

GLP-1 therapies are also approved for the treatment of type 2 diabetes, so they can be used by people with both obesity and type 2 diabetes. The safety and efficacy for use by type 1 diabetics have not been studied yet.

How does the physician consultation occur?

To complete a consultation, you will be required to answer a brief online medical questionnaire.

Your information will then be reviewed by a licensed physician, who will confirm your eligibility for treatment, and will write a prescription for those who meet the criteria.

Is my order confidential?

Our services are confidential, and your medical information and order history can only be viewed by our team of medical professionals and pharmacists. You can view our Privacy Policy for more information.

Do I need a prescription?

GLP-1 therapies do require a prescription. If you're eligible for treatment based on your answers to our medical questionnaire, our medical providers will issue you a private prescription for the therapy they believe is the best fit for you.

How do I store my medication and prevent contamination of the vial?

Be sure to store your medication in the refrigerator…BUT DO NOT FREEZE. Also be sure to wipe the rubber stopper with an alcohol pad BEFORE EVERY INJECTION.

What will the credit card charge show?

Card payments will be shown under the name Kiaora or BSC Medco

Do you take insurance for the purchase of GLP-1 therapies?

Insurance companies generally only cover these therapies for those with type 2 diabetes, so we are unable to take insurance for GLP-1 therapies.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose may cause severe nausea, vomiting, or low blood sugar.

*It is essential to note that while GLP-1s can contribute to weight loss, they should not be solely relied upon as a standalone solution. These therapies are typically prescribed as part of a comprehensive weight loss plan that includes a balanced diet, regular exercise, and healthy lifestyle choices. Working closely with a healthcare professional is important to receive appropriate guidance, monitor potential side effects, and determine the right dosage for optimal results.

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Please note that Pearl and Serene are not physicians or clinicians. The information they provide is based on conversations with physicians and extensive research and should not be construed as medical advice. Anyone considering our program will undergo evaluation by a team of qualified physicians to determine their suitability for therapy.

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